Acetone hydrazone. , round-bottomed flask containing 145 g.

Acetone hydrazone lookchem Also offer free database of Acetone hydrazone(5281-20-9) including Basic information, Chemical Property, Safety Information, Msds, Uses, Suppliers, Synthetic Route, Refernces and Doi Number etc. The hydrolysis of each adduct was catalyzed by acid. UN Number: 1090. Our findings demonstrate that this compound has strong blue-green fluorescence specifically in the presence of Hg 2+ within an acetonitrile, highlighting its potential application in That is followed by ammonolysis to the hydrazone, a process that couples two nitrogen atoms. Hydrazine is mainly used as a foaming agent in preparing polymer foams, but applications also include its uses as a Sep 25, 2024 · Oxime and hydrazone reactions: Essential bioconjugation tools that form stable bonds between aldehydes and aminooxy or hydrazide groups. Acetone hydrazone can be produced on large scale by reaction of acetone azine with hydrazine, a more convenient reaction than direct reaction of acetone and hydrazine. ), ammonia (2 eq. This process provides a new horizon for the development of catalytic acceptorless dehydrogenative coupling reactions. S-HyNic (succinimidyl 6-hydrazinonicotinate acetone hydrazone) is used to incorporate aromatic hydrazine linkers on biomolecules. However, the NIST database [6], surprisingly, contains information about only one of the simplest representatives of this class, acetone hydrazone. In this reaction, hydrazine reacts with acetone to form an imhine intermediate, which then undergoes hydrolysis to produce a setone product. The anticancer properties of these compounds are also tested against colon carcinoma cells and breast carcinoma cells. 2001 IUPAC Standard InChI: InChI=1S/C9H10N4O4/c1-6 (2)10-11-8-4-3-7 (12 (14)15)5-9 (8)13 (16)17/h3-5,11H,1-2H3 Copy The vessel was cooled down to 0° C. It is an intermediate in the synthesis of 2-diazopropane [fr]. Abstract 0 The pharmacokinetics of hydralazine acetone hydrazone (HAH), which is a metabolite of hlydralazine (HP), was investigated after iv administration to rats. 5 Oct 14, 2021 · 1 (2H)-Phthalazinone, (1-methylethylidene)hydrazone | C11H12N4 | CID 41772 - structure, chemical names, physical and chemical properties, classification, patents Preparation of Acetone hydrazone hydrazone (CAS NO. This hydrazone reacts with one more equivalent of acetone, and the resulting azine is hydrolyzed to give hydrazine, regenerating acetone. Day M. The ethanal [1] is protonated to form its conjugate acid [4]. Further pairs of isomers of diaziridines and hydrazones are known. S-4FB 2 (succinimidyl May 5, 2023 · Compounds of this class are well known and are, for example, intermediate products in the reduction of carbonyl compounds with hydrazine hydrate to isostructural hydrocarbons (the Kizhner–Wolff reaction) [3 – 5]. Articles of Acetone 2,4- (dinitrophenyl)hydrazone are included as well. Apr 15, 2001 · Preparative Methods: 1 is best prepared by either of two methods: from the acetone azine 7 or by an exchange reaction between Hydrazine and 3 in the presence of glacial acetic acid. In this study, we report the synthesis of hydrazone derived from fluorescein hydrazide and acetone as a fluorescent probe for detecting Hg 2+ in solution. For example, 3,3-dimethyldiaziridine has a heat of combustion of about 35 kcal higher than the isomeric acetone hydrazone. 05 g/mol Hydralazine acetone hydrazone | C11H12N4 | CID 41772 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. You can buy high quality, low price 5281-20-9 (acetone hydrazone) here. We also provide a 5281-20-9 (acetone hydrazone) database free of charge, including basic information, chemical properties, uses, relevant articles, Process route, upstream products and downstream products etc. Abstract Synthesis of hydrazones (1a–4a and 1b–4b), quinazolines (3c·MeOH and 3d·MeOH), and hydrazone-Schiff bases (4c and 4d) is achieved by combining suitable aldehydes (2,3- or 2,4-dihydroxybenzaldehyde) with four hydrazides (isonicotinic, nicotinic, and 2- or 4-aminobenzoic acid hydrazide). 106196404 Chemical Formula C 11 H 12 N 4 InChI Key AKFJXINWDQGPHO-UHFFFAOYSA-N InChI Acetone hydrazone CAS#5281-20-9 The Global Chemical Inventory Search (GCIS) allows you to search for the latest global chemical inventory by entering CAS No. ) The distillate boils at 114–116° and the yield is 95–97% (Note 6). Articles of Acetone (4-Chlorophenyl)hydrazone are included as well. Acetone 2,4-Dinitrophenylhydrazone showed inhibitory activi ty towards soybean lipoxygenase and renal prostaglandin synthetase. , China and India manufacturer of succinimidyl 6-hydrazinonicotiniate acetone hydrazone CAS:362522-50-7 Laboratory in Ningbo Aug 25, 2025 · Chemsrc provides CAS#:362522-50-7 MSDS, density, melting point, boiling point, structure, etc. 11 g/mol. May 20, 2025 · Acetone azine - cas 627-70-3, synthesis, structure, density, melting point, boiling point Hydrazones and oximes are common conjugates, but are labile to hydrolysis. It is intended to provide guidance for analysts needing to develop procedures to control such impurities, particularly where this is due to concerns relating to their Hydrazine Hydrazine IUPAC name Hydrazine Identifiers CAS number 302-01-2 RTECS number MU7175000 Properties Molecular formula N2H4 Molar mass 32. . With a slow rate of distillation, disproportionation occurs and the yield of acetone hydrazone is reduced. This compound features a five-membered ring structure formed by the interaction of acetone’s carbonyl group with hydrazine’s nitrogen atoms . We provide 2-Propanone, hydrazone 5281-20-9 safety data sheet view and download for free at Echemi. Finally, the (gas phase) structure of compound 3 was optimized using DFT calculations (B3LYP/6-31+G (d, p)) and its NBO charges are reported. The important polarity of the carbonyl carbon of favors hydrazine attack for forming the Jul 15, 2019 · Look through 2-Propanone, hydrazone MSDS details show. Then, the acetone hydrazone Me 2 C=N–NH 2 is formed (VIIIMe) in Figure 3. Likewise, it is susceptible Apr 15, 2001 · Preparative Methods: 1 is best prepared by either of two methods: from the acetone azine 7 or by an exchange reaction between Hydrazine and 3 in the presence of glacial acetic acid. This involves binding to the water-oxidizing complex (WOC), followed by photoreversible reduction of manganese (loss of the S1----S2 reaction). A five-co … 025-86957866 13952093866 产品介绍： 中文名称： 对-丙腙基吡啶甲酸N-羟基琥珀酰亚胺酯 英文名称： succinimidyl 6-hydrazinonicotinate acetone hydrazone CAS： 362522-50-7 纯度： 97% at less 包装信息： 5G 10G 100G 1KG ChemicalBook 为您提供6-丙酮腙基烟酸琥珀酰亚胺酯 (SANH)的化学性质，熔点，沸点，密度，分子式，分子量，物理性质，毒性，结构式，海关编码等信息，同时您还可以浏览6-丙酮腙基烟酸琥珀酰亚胺酯 (SANH)产品的价格，供应商，贸易商，生产企业和生产厂家，最后6-丙酮腙基烟酸琥珀酰亚胺酯 (SANH)的 A hydrazone is a dehydration product formed by the reaction of a hydrazine or hydrazide group with an aldehyde or ketone. CAS number: 67-64-1. May 20, 2025 · acetone hydrazone is a compound with the formula C3H8N2 and the molecular weight 72. , lysines) on biomolecules and surfaces to HyNic groups. ) and hydrogen peroxide (1 eq. The reaction con-ditions for the modification of the BCA molecule with succinimidyl 6-hydrazinonicotinate acetone hydrazone (S-HyNic) to obtain BCA-HyNic were also optimized. It is also known as isopropylidene-hydrazine propan-2-one hydrazone or propan-2-ylidenehydrazine. chemeo. com. Aldrich-273155; Acetone azine 0. SANH (succinimidyl 4-hydrazinonicotinate acetone hydrazone) and SHNH (succinimidyl hydraziniumnicotinate hydrochloride) are both hydrazine derivatives of nicotinic acid, while SHTH (succinimidyl 4-hydrazidoterephthalate hydrochloride) is a hydrazide derivative of terephthalate. Stereoisomers can exist in the case of which of the following? A) The hydrazone of butanone B) The oxime of acetone C) The phenylhydrazone of cyclohexanone The cyclic acetal formed from propanal and ethane-1,2-diol E) The imine of cyclopentanone o@ Generated by Cheméo on 2025-10-23 21:52:29. 5 g. Wang, J. Welcome to contact us for succinimidyl 6-hydrazinonicotiniate acetone hydrazone COA or MSDS. Synthesis of 2,6-diacetylpyridine-bis(benzyl and acetone )hydrazone (hereafter) designated as ligand-A and -B was carried out in two steps. Information on this page: Mass spectrum (electron ionization) References Notes Other data available: IR Spectrum Gas Chromatography Options: Switch to calorie-based units ChemSpider record containing structure, synonyms, properties, vendors and database links for Acetone 2,4-(dinitrophenyl)hydrazone, 1567-89-1, YGIXYAIGWMAGIB-UHFFFAOYSA-N The National Center for Biotechnology Information provides access to biomedical and genomic information to advance science and health. ChemicalBook provide Chemical industry users with acetone hydrazone Boiling point Melting point,acetone hydrazone Density MSDS Formula Use,If You also need to acetone hydrazone Other information,welcome to contact us. and the mixture was stirred for 10 minutes. 98; CAS Number: 627-70-3; Linear Formula: (CH3)2C=NN=C(CH3)2; find related products, papers, technical documents, MSDS & more at Sigma-Aldrich. Jan 27, 2025 · Uses Acetone 2,4-Dinitrophenylhydrazone is a dinitrophenylhydrazone (DNPH) derivative of an aliphatic ketone found in mainstream cigarette smoke. F. 4-a)phthalazine and the acetone hydrazone (HP-AH), were more potent (five- and 10-fold, respectively) than hydralazine in inhibiting potassium-induced vasoconstriction. Citations are the number of other articles citing this Get to learn about properities of 2-Propanone, hydrazone 5281-20-9. , 2. B. S-HyNic is an amino-reactive reagent that directly converts amino groups on biomolecules and surfaces to HyNic groups. 2‐Propanone, hydrazone Volume 50 A. Dec 6, 2017 · Materials and methods Materials Branched PEI (molecular weight [MW] 25 kDa) was purchased from Sigma-Aldrich (St Louis, MO, USA). Information on this page: Notes Other data available: Phase change data Gas phase ion energetics data Mass spectrum (electron ionization) Gas Chromatography Options: Switch to calorie Apr 2, 2012 · Keywords: COBALT ADHESION PROMOTER COBALT-CHELATE COMPLEX LIGAND COBALT SALICYLALDEHYDE P-PHENYLENE DIAMINE COMPLEX COBALT ACETYL ACETONE HYDRAZONE COBALT PHENYL ACETONE HYDRAZONE Obtain permissions instantly via Rightslink by clicking on the button below: Jan 27, 2025 · ACETONE AZINE (CAS 627-70-3) information, including chemical properties, structure, melting point, boiling point, density, formula, molecular weight, uses, prices The two main reactions are the formation and hydrolysis of acetone azine: The formation of azine is not a means of trapping the hydrazine formed in the Raschig process with acetone, the reaction proceeding by way of two distinct intermediates: dimethyl oxazirane and acetone hydrazone, as follows: Apr 5, 2011 · This is the latest of a series of reviews focused on the analysis of genotoxic impurities. : ). Preparation of Acetone hydrazone hydrazone (CAS NO. Chem. The nitrogen atom in hydrazine attacks the carbonyl carbon (C=O) of acetone. The compound can also be used to 2-Propanone, hydrazone Formula: C 3 H 8 N 2 Molecular weight: 72. when combined with acetone, it produces a reliable hydrazine by-product that can be easily purified. It is a simple pnictogen hydride, and is a colourless flammable liquid with an ammonia -like odour. 11 g/mol Cas Number: 5281-20-9 EINECS Number: - 1-phenylethanone hydrazone Molecular Formula: C 8 H 10 N 2 Molecular Weight: 134. Unlike the Raschig process, this process does not produce salt. ChemicalBook 致力于为化学行业用户提供6-丙酮腙基烟酸琥珀酰亚胺酯 (SANH)的性质、化学式、分子式、比重、密度,同时也包括6-丙酮腙基烟酸琥珀酰亚胺酯 (SANH)的沸点、熔点、MSDS、用途、作用、毒性、价格、生产厂家、用途、上游原料、下游产品等信息。 To understand the action of hydrazine (N2H4) on acetone (C3H6O), we can break down the process into several steps: 1. Although the mechanism is analogous to that of imine formation, we will discuss the steps again. The spectrum eliminates both the It can also be produced from acetone (2 eq. The new compound has various potential applications, including serving as a precursor for pharmaceuticals. S-HyNic 1 (succinimidyl 6-hydrazinonicotinate acetone hydrazone, SANH) is used to incorporate aromatic hydrazine linkers on biomolecules. [4] Azines are also produced when chalcone reacts with a hydrazone to produce 3,5-diphenyl-1 H - pyrazole, [5] in a conversion also carried out with Showing metabocard for Hydralazine acetone hydrazone (HMDB0060606) Jump To Section: Identification Taxonomy Ontology Physical properties Spectra Biological properties Concentrations Links References XML Acetone (1-methylethylidene)hydrazone - References EPA chemical substance information information is provided by: ofmpeb. Ideal for protein labeling, drug delivery, and surface modification under mild conditions, enhancing biomedical research and therapeutic applications. grade. Sep 22, 2025 · Chemsrc provides Acetone (4-Chlorophenyl)hydrazone (CAS#:1200-11-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Metabolite Hydralazine acetone hydrazone Name Hydralazine acetone hydrazone Description Not Available Structure Download Similar Structures Synonyms Not Available UNII Not Available CAS number Not Available Weight Average: 200. Cheméo (https://www. Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. R. [3] In the laboratory, azines are typically prepared by condensation of hydrazine with two equivalents of a carbonyl. Sun, N. S-4FB (succinimidyl 4-formylbenzoate) is used to convert amino groups to aromatic aldehydes (4-formylbenzamide, or 4FB groups). (Caution! Distillation in air can lead to explosion. The hydrazine reaction creates a reliable material that could be utilized in several applications. The general formula for acetone In this study, we report the synthesis of hydrazone derived from fluorescein hydrazide and acetone as a fluorescent probe for detecting Hg 2+ in solution. A 500-ml. It is characterized by the presence of a hydrazone functional group, where a nitrogen atom from hydrazine is bonded to the carbon atom of the carbonyl group in acetone, resulting in a five-membered ring structure. 0–9. Addition Jan 5, 2019 · ABSTRACT An alternative variation of the most common preparation of 2,4-dinitrophenylhydrazine reagent is presented. Identify the Reactants: - Acetone is represented as CH3COCH3 or C3H6O. The hydrazones are then eluted and analyzed by high-performance liquid chromatography (HPLC) using a UV detector. This method is suitable for scaling up for quantities required for preparing stock reagent for classes. Fischer represented the hydrazones and osaz… Question: 100. 21 mole) of acetone hydrazone (Note 4) is added dropwise through the funnel (Note 5). Reaction of Aldehydes or Ketones with Hydrazine Produces a Hydrazone Reaction with a Base and Heat Converts a Hydrazone to an Alkane Both Reactions Together Produces the Wolff-Kishner Reduction Example Aug 21, 1990 · Acetone hydrazone (AceH), (CH3)2CNNH2, inhibits water oxidation by a mechanism that is analogous to that of NH2OH. 50 moles) of acetone is fitted with a mechanical stirrer and a dropping funnel and cooled in an ice bath. ChemSpider record containing structure, synonyms, properties, vendors and database links for Acetone phenylhydrazone, 103-02-6, JQLKSEQEILIJEG-UHFFFAOYSA-N Acetone hydrazone, also known as isopropylidenehydrazine, is the product of condensation of acetone and hydrazine . It is an intermediate in the synthesis of 2-diazopropane . 180858309 +0000 UTC m=+1004546. (183 ml. Acetone azine (CAS NO. Acetone, (2,4-dinitrophenyl)hydrazone Formula: C 9 H 10 N 4 O 4 Molecular weight: 238. Anhydrous hydrazine is prepared by heating under reflux 100% hydrazine hydrate with an equal weight of sodium hydroxide pellets for 2 hours, followed by distillation in a slow stream of nitrogen introduced through a capillary leak. Acetone hydrazone (isopropylidenehydrazine) is the product of condensation of acetone and hydrazine, as typical for hydrazone formation. , and with vigorous stirring 15 g. , 2014, 79, 8031 The hydrazones [3] are obtained by reaction of aldehydes or ketones [1] with hydrazine [2]. It is a type of Schiff base that is more stable than standard imines due to its resistance to hydrolysis, making it a valuable linkage in various chemical reactions. C6-S-HyNic (C6-succinimidyl 6-hydrazinonicotinate acetone hydrazone [C6-SANH]) was purchased from Solulink (San Diego, CA, USA). We sell pure Succinimidyl 6-hydrazinonicotinate acetone hydrazone 362522-50-7 SANH for a price of 300 € for 100 mg EXW; available from stock Acetone hydrazone from acetoneAnhydrous hydrazine is prepared byheating under reflux 100 hydrazine hydrate with an equal weight of sodium hydroxide pellets for two A useful variant of the imine-forming reaction just discussed involves the treatment of an aldehyde or ketone with hydrazine, H2N–NH2, in the presence o Acetone hydrazone, a colorless, oily liquid, is a chemical compound derived from the reaction of acetone and hydrazine. Since the action of 2, 4-dinitrophenylhydrazine (Brady’s reagent) on aldehydes and ketones was first investigated by Purgotti in 1894, its usefulness as an analytical The Carcinogenic Potency Database (CPDB) is a unique and widely used international resource of the results of 6540 chronic, long-term animal cancer tests on 1547 chemicals. g. S-HyNic (Succinimidyl 6-hydrazinonicotinate acetone hydrazone) is a heterobifunctional linker used for introducing protected hydrazinonicotinamide functional groups (HyNic) onto proteins and other primary amine-containing biological molecules through a reactive N-hydroxysuccinimide (NHS) ester. 31 Experimental All the chemicals used were of A. 3 Recent Literature A catalytic acceptorless dehydrogenative coupling of arylhydrazines and alcohols enables a direct synthesis of arylhydrazones with complete selectivity for arylhydrazones without N-alkylated byproducts. For example, dinitrophenylhydrazine coated onto a silica sorbent is the basis of an adsorption cartridge. 64 moles) in 40 ML of methanol was added drop-wise over 1 hour at 5° C. Acetone hydrazone. Reaction of acetone with hydrazine gives propan -2-ylidene hydrazine, a simple hydrazone. This review summarises the analytical approaches reported in the literature relating to hydrazine, hydrazines, hydrazides and hydrazones. A. The hydrolytic stability of isostructural hydrazones and an oxime have been determined at pD 5. 1090 IUPAC Standard InChI: InChI=1S/C3H8N2/c1-3 (2)5-4/h4H2,1-2H3 Copy Sheet of paper on top of another sheet Apr 15, 2001 · Preparative Methods: 1 is best prepared by either of two methods: from the acetone azine 7 or by an exchange reaction between Hydrazine and 3 in the presence of glacial acetic acid. Reaction of benzaldehyde with 2,4-di nitro phenyl hydrazine (2,4-DNPH) gives 1- benzyl idene-2- (2,4-di nitro phenyl) hydrazine. Articles of Acetone diisobutyl hydrazone are included as well. Aldehydes and ketones can be converted to a hydrazone derivative by reaction with hydrazine. Talseth T, McNay JL, Haegele KD: Hypotensive effect of the hydralazine--acetone hydrazone in conscious rabbits: evidence for its back-conversion to hydralazine in vivo. Hydrazone formation is a variation of the imine forming reaction discussed in the previous section. This involves binding to the water-oxidizing complex (WOC), followed by photoreversible reduction of manganese (loss of the S 1 → S 2 reaction). Hydrazones derived from 2,4-DNPH are often colored (red or orange) due to extensive conjugation. (1. Its name is 2,5-dioxopyrrolidin-1-yl 6- (2- (propan-2-ylidene)hydrazinyl)nicotinate (S-SANH) Find quality suppliers and manufacturers of Acetone hydrazone for price inquiry. [7] Hydrazones are the basis for various analyses of ketones and aldehydes. The formation of oximes and hydrazones is employed in numerous scientific fields as a simple and versatile conjugation strategy. 02 Read the full text About Tools Share S-HyNic (succinimidyl 6-hydrazinonicotinate acetone hydrazone) is used to incorporate aromatic hydrazine linkers on biomolecules. A solution of acetone (37 g, 0. org/10. , lysines) on biomolecules and 6-hydrazinonicotinate acetone hydrazone) is a water-soluble version of S-HyNic which is used to incorporate aromatic hydrazine linkers on biomolecules and surfaces. Li, C. Only one value of its gas The pressure throughout the system is reduced to 250 mm. 710898973. ). Information on this page: IR Spectrum References Notes Other data available: Mass spectrum (electron ionization) Gas Chromatography Options: Switch to calorie-based units Introduction SoluLINK® bioconjugation technology is based on the formation of a stable covalent bond between an aromatic hydrazine and an aromatic aldehyde. Stirring was continued, allowing the reaction to warm slowly to room temperature. Dec 19, 2024 · acetone hydrazone (CAS 5281-20-9) information, including chemical properties, structure, melting point, boiling point, density, formula, molecular weight, uses Aug 19, 2022 · Acetone hydrazone is a dependable material utilized in many different requests. where to buy Acetone hydrazone(5281-20-9). With vigorous stirring, 65. Plasma concentrations of HAH, HP, and hydralazine pyruvic acid hydrazone (HPH) were simultaneously determined by a specific HPLC method. Other names: Acetone, azine; Acetone ketazine; Dimethyl ketazine Permanent link for this species. 181 g/mol Cas Number: 13466-30-3 EINECS Number: - 1,1,1,3,3,3-hexafluoroacetone hydrazone Molecular Formula: C 3 H 2 F 6 N 2 Molecular Weight: 180. May 16, 2023 · The reaction conditions for the modification of the BCA molecule with succinimidyl 6-hydrazinonicotinate acetone hydrazone (S-HyNic) to obtain BCA-HyNic were also optimized. Sulfo S-HyNic is an amine-reactive linker that directly converts amino groups to HyNic groups. 1090 IUPAC Standard InChI: InChI=1S/C3H8N2/c1-3 (2)5-4/h4H2,1-2H3 Copy Sheet of paper on top of another sheet Sep 15, 2025 · 2-Propanone, 2-phenylhydrazone | C9H12N2 | CID 66026 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological Other names: 2-Propanone, (2,4-dinitrophenyl)hydrazone Permanent link for this species. Substance names and other identifiers Expand all Collapse all Regulatory process names Acetone hydrazone EC Inventory acetone hydrazone Pre-Registration process BOC Sciences is the world-leading provider of special chemicals. The pharmacokinetics of hydralazine acetone hydrazone (HAH), which is a metabolite of hydralazine (HP), was investigated after iv administration to rats. ChemicalBook 致力于为化学行业用户提供丙酮腙的性质、化学式、分子式、比重、密度,同时也包括丙酮腙的沸点、熔点、MSDS、用途、作用、毒性、价格、生产厂家、用途、上游原料、下游产品等信息。 Sep 15, 2019 · Both hydrazone ligands and their Co (III) complexes exhibit antibacterial and antifungal activities, but the Co (III)-hydrazone complexes act as more potent bactericidal agents than the hydrazone ligands and metal salt. Aug 25, 2025 · Chemsrc provides Acetone 2,4- (dinitrophenyl)hydrazone (CAS#:1567-89-1) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Rate constants for Other names: 2-Propanone, (2,4-dinitrophenyl)hydrazone Permanent link for this species. In this video I have discussed about the reaction of acetone with phenyl hydrazine. , round-bottomed flask containing 145 g. AI generated definition based on: Bioconjugate Techniques (Third Edition), 2013 Aug 19, 2017 · Find Safety Data Sheets (SDS) of acetone hydrazone (CAS 5281-20-9 ) for lookchem Jump To Section: Identification Taxonomy Ontology Physical properties Spectra Biological properties Concentrations Links References XML Acetone Alternative Names: 2-Propanone, Dimethyl formaldehyde, Dimethyl ketone, Propanone, Pyroacetic spirit (archaic), ²-Ketopropane. Chemical and physical properties of Acetone, (2,4-dinitrophenyl)hydrazone. The overall knowledge and encyclopedia of 2-Propanone, hydrazone covering characteristics, safety, 2-Propanone, hydrazone usage, MSDS/SDS and more. 1090 IUPAC Standard InChI: InChI=1S/C3H8N2/c1-3 (2)5-4/h4H2,1-2H3 Copy Apr 15, 2001 · Preparative Methods: 1 is best prepared by either of two methods: from the acetone azine 7 or by an exchange reaction between Hydrazine and 3 in the presence of glacial acetic acid. A five-compartment pharmacokinetic model was presented to elucidate the disposition of Acetone hydrazone (C₃H₈N₂) is a hydrazone derivative synthesized via the reaction of acetone with hydrazine (N₂H₄) . com) is the biggest free database of chemical and physical data for the process industry. 2001 IUPAC Standard InChI: InChI=1S/C9H10N4O4/c1-6 (2)10-11-8-4-3-7 (12 (14)15)5-9 (8)13 (16)17/h3-5,11H,1-2H3 Copy General hydrazone structur e. The other metabolites produced less than 50% inhibition at the highest concentration tested. or name of substances in both Chinese and English. determining. Hydrazine is an inorganic compound with the chemical formula N 2 H 4. Routes of the conversion of the hydrazone to the trans -diimine were obtained in the sequence, hydrazone (VIIIMe) → TS4 (IXMe) → hydrazone anion (XMe) → TS5 (XIMe) → trans -diimine (XIIMe) in Figure 3. Whiting First published:28 April 2003 https://doi. It plays a crucial role in the fields of pharmaceuticals, agrochemicals, and materials science. Reaction Mechanism: - When hydrazine reacts with acetone, it acts as a nucleophile. Use this link for bookmarking this species for future reference. Org. 1002/0471264180. : ), which is known as 2-Propanone, hydrazone, could be produced through the following synthetic routes. - Hydrazine is represented as N 2H4. 2. Download scientific diagram | Scheme 1: Reaction of phenylhydrazine with acetone from publication: Synthesis and Antimicrobial Evaluation of Some Simple Phenylhydrazones | The frequency of relapse We are a quality supplier and manufacturer of 5281-20-9. Formula: (CH 3) 2 CO. [citation needed] The compound Acetone hydrazone CAS#5281-20-9 The Global Chemical Inventory Search (GCIS) allows you to search for the latest global chemical inventory by entering CAS No. [4] The first step is the formation of acetone imine, Me 2 C=NH; this is then oxidized by hydrogen peroxide through a complex mechanism to give 3,3-dimethyloxaziridine, which reacts with a further molecule of ammonia to produce acetone hydrazone. Plasrna concentrations of HAH, HP, and hydralazine pyruvic: acid hydrazone (HPH) were simultaneously deter- mined by a specific HPLC method. Information on this page: IR Spectrum References Notes Other data available: Mass spectrum (electron ionization) Gas Chromatography Options: Switch to calorie-based units S-HyNic 1 (succinimidyl 6-hydrazinonicotinate acetone hydrazone, SANH) is used to incorporate aromatic hydrazine linkers on biomolecules. Pigment Yellow 97, a popular yellow colorant, is a hydrazone. 2-Propanone, hydrazone | C3H8N2 | CID 78937 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. May 7, 2021 · Acetone hydrazone monohydrate | C3H10N2O | CID 129805409 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. S-HyNic is an amine-reactive linker that directly converts amino groups (e. However, it is The usual method of industrial production is the peroxide process, starting from the ketone, ammonia, and hydrogen peroxide. Our findings demonstrate that this compound has strong blue-green fluorescence specifically in the presence of Hg 2+ within an acetonitrile, highlighting its potential application in acetone hydrazone Molecular Formula: C 3 H 8 N 2 Molecular Weight: 72. os050. When acetone reacts with phenyl hydrazine we get acetone phenyl hydrazone. The CPDB provides easy access to the bioassay literature, with qualitative and quantitative analyses of both positive and negative experiments that have been published over the past 50 years in the general literature Acetone hydrazone (AceH), (CH 3) 2 CNNH 2, inhibits water oxidation by a mechanism that is analogous to that of NH 2 OH. epa. NMR of the precipitate showed mostly hydrazone, the conversion is close to100% by weight NMR of supernatant showed ~30% of unreacted sample, hydrazone and acetone azine formed due to the Acetazine | C6H12N2 | CID 79085 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety Nov 16, 2011 · The structure of hydrazone 3 is discussed in detail and compared to that of monoformylhydrazine. This chapter discusses the structure and reactivity of the hydrazone and osazone derivatives of the sugar. Product Description: Succinimidyl 6-hydrazinonicotinate acetone hydrazone (SANH) is a heterobifunctional linker used for introducing protected hydrazinonicotinimide functional groups into proteins, peptides, surfaces and other primary amine containing molecules via its reactive N-hydroxysuccinimide ester terminus. Hydrazine is highly hazardous unless handled in solution as, for example, hydrazine hydrate (N2H4·xH2O). ChemSpider record containing structure, synonyms, properties, vendors and database links for acetazine, 627-70-3, PFLUPZGCTVGDLV-UHFFFAOYSA-N ChemicalBook 为您提供6-丙酮腙基烟酰氨基己酸琥珀酰亚胺酯 (937249-76-8)的化学性质，熔点，沸点，密度，分子式，分子量，物理性质，毒性，结构式，海关编码等信息，同时您还可以浏览6-丙酮腙基烟酰氨基己酸琥珀酰亚胺酯 (937249-76-8)产品的价格，供应商，贸易商，生产企业和生产厂家，最后6-丙酮腙 Two metabolites, 9-hydroxy-3-methyl-s-triazolo- (3. A suite of approaches for their preparation is described: solution-based synthesis Jan 23, 2014 · Then, the acetone hydrazone Me 2 C=N–NH 2 is formed (VIIIMe) in Figure 3. This imine-forming reaction is applied in fields as diverse as polymer chemistry, biomaterials and hydrogels, dynamic Acetone hydrazone (isopropylidenehydrazine) is the product of condensation of acetone and hydrazine, as typical for hydrazone formation. ChemSpider record containing structure, synonyms, properties, vendors and database links for acetone hydrazone, 5281-20-9, JIQXKYSNGXUDJU-UHFFFAOYSA-N Acetone hydrazone condenses with another acetone molecule to give acetone azine, where two acetone units are linked through a –N=N– group. Where to buy Acetone in the USA We have compiled a list of Acetone suppliers in USA, the companies listed have a genuine United States presence and include: distributors, wholesalers, industrial 1 (succinimidyl 6-hydrazinonicotinate acetone hydrazone, SANH) is used to incorporate aromatic hydrazine linkers on biomolecules. Other names: 2-Propanone, (2,4-dinitrophenyl)hydrazone Permanent link for this species. These metrics are regularly updated to reflect usage leading up to the last few days. (0. 6, 8 Both methods give nearly quantitative yields of 1, but the latter method produces hydrazone without azine contamination. As in the case of imines and oximes, it requires pH=4. gov (external link) Last Update：2024-04-09 15:16:58 View Acetone (1-methylethylidene)hydrazone structural formula Introduction SoluLINK bioconjugation technology is based on the formation of a stable covalent bond between an aromatic hydrazine and an aromatic aldehyde. 2398 Monoisotopic: 200. 0. The hydrazone structure 40 can be eliminated at once many examples of this class of compounds are known and their properties are completely different from the diaziridines. Sep 19, 2025 · Chemsrc provides Acetone diisobutyl hydrazone (CAS#:52835-12-8) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Upon deprotection of the hydrazone functionality under acidic or neutral pH (4. Stirring was continued overnight, but if the reaction was allowed to proceed for p-Toluenesulfonyl acetone hydrazone 3900-79-6 p-Toluenesulfonyl acetone hydrazone (CAS 3900-79-6, C10H14N2O2S), is a white crystalline solid, widely used in organic synthesis, with the special property of being a versatile reagent for the preparation of various compounds. 31 Acetone hydrazone, also known as isopropylidenehydrazine, is an organic compound formed through the condensation reaction of acetone and hydrazine. , lysines) on biomolecules and Increasing the number of electron-accepting groups in the phenylhydrazone molecule improves its stability to acid hydrolysis45'48: for example, acetone 2,4-dinitrophenyl-hydrazone remains unchanged under conditions such that the phenylhydrazone is completely hydrolysed45. 2-Propanone, hydrazone Formula: C 3 H 8 N 2 Molecular weight: 72. C. Dox was purchased from Meilun Biology Technology (Dalian, China). If the forerun and material boiling above 126° are combined and reheated at 100° for 12–16 hours, they give more acetone hydrazone on redistillation. Additionally, it serves as a stabilizer in some polymers and as a corrosion inhibitor for metals. It is commonly used as a reagent in organic synthesis, particularly in the formation of hydrazones and as a precursor to various hydrazine-containing compounds. We offer qualified product acetone hydrazone (5281-20-9), please inquire us for acetone hydrazone (5281-20-9). May 7, 2021 · Acetone (1-methylidene)hydrazone | C4H8N2 | CID 15898177 - structure, chemical names, physical and chemical properties, classification, patents, literature Succinimidyl 6-hydrazinonicotinate acetone hydrazone (SANH; S-HyNic) is a heterobifunctional linker used for introducing protected hydrazinonicotinimide functional groups into proteins, peptides, surfaces and other primary amine containing molecules via its reactive N-hydroxysuccinimide ester terminus. mmap cpyqz nuw dddwk tmaegi swrzza arokelrv sojpl qbuitug kppf qebvhv rbi ymokld kegss qedpc